"Teacher, when will this be ... ?" (21:7)
And the first thing Jesus says is telling us not to be misled. (21:8) In response, Jesus doesn't go into a discussion about the sign of the end. He does that next, but first, he tells his disciples not to be led astray. It is only after warning us not to be misled that Jesus speaks a little about the signs. (21:9-11; 25-28) And notice that when he does speak of the end how very general these signs are. Despite the tendency for some to equate a conflict or natural disaster with the end, Jesus makes it difficult to correlate events in history and the end by speaking in general terms of the end. But then he says,
"But before all this occurs... "
And he mentions two sets of occurrences to occur before the end, that is, they are not signs of the end. The first is persecution. (21:12-19) By the time of Luke, this has/is happening. And the other is the siege of Jerusalem by the Romans. (21:20. Compare Mark 13:14) Again, by the time of Luke this is most likely in the past. So Jesus is explicitly separating out these dateable events (persecution and siege) from the more generalised signs earlier mentioned. That these events have taken place strengthens the prophetic credentials of Jesus. But it also gives us an added warning against too easily correlating earth-shattering events in history, in our society, or in our lives with 'the end'.